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Porous nanocellulose gels and foams : Breakthrough status in the development of scaffolds for tissue engineering

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dc.contributor Aalto-yliopisto fi
dc.contributor Aalto University en
dc.contributor.author Ferreira, Filipe V.
dc.contributor.author Otoni, Caio G.
dc.contributor.author De France, Kevin J.
dc.contributor.author Barud, Hernane S.
dc.contributor.author Lona, Liliane M.F.
dc.contributor.author Cranston, Emily D.
dc.contributor.author Rojas, Orlando J.
dc.date.accessioned 2020-09-11T06:30:15Z
dc.date.available 2020-09-11T06:30:15Z
dc.date.issued 2020-07-01
dc.identifier.citation Ferreira , F V , Otoni , C G , De France , K J , Barud , H S , Lona , L M F , Cranston , E D & Rojas , O J 2020 , ' Porous nanocellulose gels and foams : Breakthrough status in the development of scaffolds for tissue engineering ' , Materials Today , vol. 37 , pp. 126-141 . https://doi.org/10.1016/j.mattod.2020.03.003 en
dc.identifier.issn 1369-7021
dc.identifier.other PURE UUID: 507315eb-c9c8-419d-a853-f83647020c6a
dc.identifier.other PURE ITEMURL: https://research.aalto.fi/en/publications/507315eb-c9c8-419d-a853-f83647020c6a
dc.identifier.other PURE LINK: http://www.scopus.com/inward/record.url?scp=85082798852&partnerID=8YFLogxK
dc.identifier.other PURE FILEURL: https://research.aalto.fi/files/51299653/1_s2.0_S1369702120300766_main.pdf
dc.identifier.uri https://aaltodoc.aalto.fi/handle/123456789/46425
dc.description | openaire: EC/H2020/788489/EU//BioELCell
dc.description.abstract We report on the latest scientific advances related to the use of porous foams and gels prepared with cellulose nanofibrils (CNF) and nanocrystals (CNC) as well as bacterial nanocellulose (BNC) – collectively nanocelluloses – as biomedical materials for application in tissue regeneration. Interest in such applications stems from the lightweight and strong structures that can be efficiently produced from these nanocelluloses. Dried nanocellulose foams and gels, including xerogels, cryogels, and aerogels have been synthesized effortlessly using green, scalable, and cost-effective techniques. Methods to control structural features (e.g., porosity, morphology, and mechanical performance) and biological interactions (e.g., biocompatibility and biodegradability) are discussed in light of specific tissues of interest. The state-of-the-art in the field of nanocellulose-based scaffolds for tissue engineering is presented, covering physicochemical and biological properties relevant to these porous systems that promise groundbreaking advances. Specifically, these materials show excellent performance for in vitro cell culturing and in vivo implantation. We report on recent efforts related to BNC scaffolds used in animal and human implants, which furthermore support the viability of CNF- and CNC-based scaffolds in next-generation biomedical materials. en
dc.format.extent 126-141
dc.format.mimetype application/pdf
dc.language.iso en en
dc.publisher ELSEVIER SCI LTD
dc.relation info:eu-repo/grantAgreement/EC/H2020/788489/EU//BioELCell
dc.relation.ispartofseries Materials Today en
dc.relation.ispartofseries Volume 37 en
dc.rights openAccess en
dc.title Porous nanocellulose gels and foams : Breakthrough status in the development of scaffolds for tissue engineering en
dc.type A2 Katsausartikkeli tieteellisessä aikakauslehdessä fi
dc.description.version Peer reviewed en
dc.contributor.department University of Campinas
dc.contributor.department Swiss Federal Laboratories for Materials Science and Technology
dc.contributor.department University of Araraquara
dc.contributor.department University of British Columbia
dc.contributor.department Department of Bioproducts and Biosystems
dc.identifier.urn URN:NBN:fi:aalto-202009115348
dc.identifier.doi 10.1016/j.mattod.2020.03.003
dc.type.version publishedVersion

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