Cyclodextrin-Functionalized Fiber Yarns Spun from Deep Eutectic Cellulose Solutions for Nonspecific Hormone Capture in Aqueous Matrices

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dc.contributor Aalto-yliopisto fi
dc.contributor Aalto University en
dc.contributor.author Orelma, Hannes
dc.contributor.author Virtanen, Tommi
dc.contributor.author Spoljaric, Steven
dc.contributor.author Lehmonen, Jani
dc.contributor.author Seppälä, Jukka
dc.contributor.author Rojas, Orlando J.
dc.contributor.author Harlin, Ali
dc.date.accessioned 2019-04-02T06:56:57Z
dc.date.available 2019-04-02T06:56:57Z
dc.date.issued 2018-02-12
dc.identifier.citation Orelma , H , Virtanen , T , Spoljaric , S , Lehmonen , J , Seppälä , J , Rojas , O J & Harlin , A 2018 , ' Cyclodextrin-Functionalized Fiber Yarns Spun from Deep Eutectic Cellulose Solutions for Nonspecific Hormone Capture in Aqueous Matrices ' Biomacromolecules , vol. 19 , no. 2 , pp. 652-661 . https://doi.org/10.1021/acs.biomac.7b01765 en
dc.identifier.issn 1525-7797
dc.identifier.issn 1526-4602
dc.identifier.other PURE UUID: bcc33884-106f-4890-b7fb-8b4b93cd8594
dc.identifier.other PURE ITEMURL: https://research.aalto.fi/en/publications/cyclodextrinfunctionalized-fiber-yarns-spun-from-deep-eutectic-cellulose-solutions-for-nonspecific-hormone-capture-in-aqueous-matrices(bcc33884-106f-4890-b7fb-8b4b93cd8594).html
dc.identifier.other PURE LINK: http://www.scopus.com/inward/record.url?scp=85041898845&partnerID=8YFLogxK
dc.identifier.other PURE FILEURL: https://research.aalto.fi/files/32536594/CHEM_Orelma_et_al_Cyclodextrin_Functionalized_2019_Biomacromolecules.pdf
dc.identifier.uri https://aaltodoc.aalto.fi/handle/123456789/37372
dc.description.abstract A wood based yarn platform for capturing pharmaceutical molecules from water was developed. Cellulose fiber yarns were modified with cyclodextrins, and the capture of 17α-ethinyl estradiol (EE2), a synthetic estrogen hormone used as contraceptive, from water was tested. The yarns were prepared by spinning a deep eutectic solution (DES) of cellulose in choline chloride-urea. Despite their high porosity and water sorption capacity (5 g/g), the spun fiber yarns displayed high wet strength, up to 60% of that recorded in dry condition (128 MPa with 17% strain at break). Cyclodextrin irreversible attachment on the yarns was achieved with adsorbed chitosan and the conjugation reactions and capture of EE2 by the cyclodextrin-modified cellulose were confirmed via online detection with Surface Plasmon Resonance (SPR). The facile synthesis of the bioactive yarns and EE2 binding capacity from aqueous matrices (as high as 2.5 mg/g) indicate excellent prospects for inexpensive platforms in disposable affinity filtration. The study presents a strategy to produce a wood fiber based yarn to be used as a platform for human and veterinary pharmaceutical hormone capture. en
dc.format.extent 10
dc.format.extent 652-661
dc.format.mimetype application/pdf
dc.language.iso en en
dc.publisher AMER CHEMICAL SOC
dc.relation.ispartofseries Biomacromolecules en
dc.relation.ispartofseries Volume 19, issue 2 en
dc.rights openAccess en
dc.subject.other Bioengineering en
dc.subject.other Biomaterials en
dc.subject.other Polymers and Plastics en
dc.subject.other Materials Chemistry en
dc.subject.other 216 Materials engineering en
dc.title Cyclodextrin-Functionalized Fiber Yarns Spun from Deep Eutectic Cellulose Solutions for Nonspecific Hormone Capture in Aqueous Matrices en
dc.type A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä fi
dc.description.version Peer reviewed en
dc.contributor.department VTT Technical Research Centre of Finland
dc.contributor.department Department of Chemical and Metallurgical Engineering
dc.contributor.department Department of Bioproducts and Biosystems
dc.subject.keyword Bioengineering
dc.subject.keyword Biomaterials
dc.subject.keyword Polymers and Plastics
dc.subject.keyword Materials Chemistry
dc.subject.keyword 216 Materials engineering
dc.identifier.urn URN:NBN:fi:aalto-201904022503
dc.identifier.doi 10.1021/acs.biomac.7b01765
dc.type.version publishedVersion


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