Drug-releasing Biopolymeric Structures Manufactured via Stereolithography

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dc.contributor Aalto-yliopisto fi
dc.contributor Aalto University en
dc.contributor.author Asikainen, Sanja
dc.contributor.author van Bochove, Bas
dc.contributor.author Seppälä, Jukka
dc.date.accessioned 2019-03-13T07:12:25Z
dc.date.available 2019-03-13T07:12:25Z
dc.date.issued 2019-01-10
dc.identifier.citation Asikainen , S , van Bochove , B & Seppälä , J 2019 , ' Drug-releasing Biopolymeric Structures Manufactured via Stereolithography ' , BIOMEDICAL PHYSICS & ENGINEERING EXPRESS . https://doi.org/10.1088/2057-1976/aaf0e en
dc.identifier.issn 2057-1976
dc.identifier.other PURE UUID: 444f4d06-fcfb-4d66-953f-97ac50dfbe1a
dc.identifier.other PURE ITEMURL: https://research.aalto.fi/en/publications/drugreleasing-biopolymeric-structures-manufactured-via-stereolithography(444f4d06-fcfb-4d66-953f-97ac50dfbe1a).html
dc.identifier.other PURE FILEURL: https://research.aalto.fi/files/29890513/CHEM_Asikainen_et_al_Drug_releasing_Biomed_Phys_2018.pdf
dc.identifier.uri https://aaltodoc.aalto.fi/handle/123456789/37096
dc.description.abstract Additive manufacturing (AM) techniques, such as stereolithography (SLA), enable the preparation of designed complex structures. AM has gained interest especially in the tissue engineering field due to the possibility to manufacture patient specific implants. However, AM could be useful also in controlled drug release applications, since the size and shape of the device, pore architecture and surface to volume ratio can be accurately designed. In this study, SLA was used to prepare polycaprolactone scaffold structures containing the model drug lidocaine. The release of lidocaine was studied and the influence of porosity and surface to volume ratio of structures to the drug release was analyzed. Porous samples released lidocaine faster compared to solid ones, whereas the degree of porosity and surface to volume ratio did not have a clear effect on the drug release profile. en
dc.format.mimetype application/pdf
dc.language.iso en en
dc.publisher Institute of Physics Publishing
dc.relation.ispartofseries BIOMEDICAL PHYSICS & ENGINEERING EXPRESS en
dc.rights openAccess en
dc.subject.other 216 Materials engineering en
dc.subject.other 215 Chemical engineering en
dc.title Drug-releasing Biopolymeric Structures Manufactured via Stereolithography en
dc.type A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä fi
dc.description.version Peer reviewed en
dc.contributor.department Polymer technology
dc.contributor.department Department of Chemical and Metallurgical Engineering en
dc.subject.keyword 216 Materials engineering
dc.subject.keyword 215 Chemical engineering
dc.identifier.urn URN:NBN:fi:aalto-201903132239
dc.identifier.doi 10.1088/2057-1976/aaf0e
dc.date.embargo info:eu-repo/date/embargoEnd/2020-01-11

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