Blume , F , Sprengart , P & Deska , J 2018 , ' Lipase-Induced Oxidative Furan Rearrangements ' Synlett , vol. 29 , no. 10 , pp. 1293-1296 . DOI: 10.1055/s-0036-1591889
Abstract:
Lipase B from Candida antarctica catalyzes the oxidative ring expansion of furfuryl alcohols using aqueous hydrogen peroxide to yield functionalized pyranones under mild conditions. The method further allows for the preparation of corresponding piperidinone derivatives by enzymatic rearrangement of N-protected furfurylamines.