Depression, depressive symptoms and treatments in women who have recently given birth

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dc.contributor Aalto-yliopisto fi
dc.contributor Aalto University en
dc.contributor.author Petersen, Irene
dc.contributor.author Peltola, Tomi
dc.contributor.author Kaski, Samuel
dc.contributor.author Walters, Kate R
dc.contributor.author Hardoon, Sarah
dc.date.accessioned 2018-11-02T08:45:21Z
dc.date.available 2018-11-02T08:45:21Z
dc.date.issued 2018-10-24
dc.identifier.citation Petersen , I , Peltola , T , Kaski , S , Walters , K R & Hardoon , S 2018 , ' Depression, depressive symptoms and treatments in women who have recently given birth: UK cohort study ' BMJ Open , vol 8 , no. 10 , e02215 , pp. 1-8 . DOI: 10.1136/bmjopen-2018-022152 en
dc.identifier.issn 2044-6055
dc.identifier.other PURE UUID: ef161b00-222c-42f7-b60f-2c5a4de72679
dc.identifier.other PURE ITEMURL: https://research.aalto.fi/en/publications/depression-depressive-symptoms-and-treatments-in-women-who-have-recently-given-birth(ef161b00-222c-42f7-b60f-2c5a4de72679).html
dc.identifier.other PURE LINK: http://dx.doi.org/10.1136/bmjopen-2018-022152
dc.identifier.other PURE FILEURL: https://research.aalto.fi/files/28945478/e022152.full.pdf
dc.identifier.uri https://aaltodoc.aalto.fi/handle/123456789/34545
dc.description.abstract Objectives: To investigate how depression is recognised in the year after child birth and treatment given in clinical practice. Design: Cohort study based on UK primary care electronic health records. Setting: Primary care. Participants: Women who have given live birth between 2000 and 2013. Outcomes: Prevalence of postnatal depression, depression diagnoses, depressive symptoms, antidepressant and non-pharmacological treatment within a year after birth. Results: Of 206 517 women, 23 623 (11%) had a record of depressive diagnosis or symptoms in the year after delivery and more than one in eight women received antidepressant treatment. Recording and treatment peaked 6-8 weeks after delivery. Initiation of selective serotonin reuptake inhibitors (SSRI) treatment has become earlier in the more recent years. Thus, the initiation rate of SSRI treatment per 100 pregnancies (95% CI) at 8 weeks were 2.6 (2.5 to 2.8) in 2000-2004, increasing to 3.0 (2.9 to 3.1) in 2005-2009 and 3.8 (3.6 to 3.9) in 2010-2013. The overall rate of initiation of SSRI within the year after delivery, however, has not changed noticeably. A third of the women had at least one record suggestive of depression at any time prior to delivery and of these one in four received SSRI treatment in the year after delivery. Younger women were most likely to have records of depression and depressive symptoms. (Relative risk for postnatal depression: age 15-19: 1.92 (1.76 to 2.10), age 20-24: 1.49 (1.39 to 1.59) versus age 30-34). The risk of depression, postnatal depression and depressive symptoms increased with increasing social deprivation. Conclusions: More than 1 in 10 women had electronic health records indicating depression diagnoses or depressive symptoms within a year after delivery and more than one in eight women received antidepressant treatment in this period. Women aged below 30 and from the most deprived areas were at highest risk of depression and most likely to receive antidepressant treatment. en
dc.format.extent 8
dc.format.extent 1-8
dc.format.mimetype application/pdf
dc.language.iso en en
dc.relation.ispartofseries BMJ Open en
dc.relation.ispartofseries Volume 8, issue 10 en
dc.rights openAccess en
dc.subject.other 113 Computer and information sciences en
dc.subject.other 3142 Public health care science, environmental and occupational health en
dc.title Depression, depressive symptoms and treatments in women who have recently given birth en
dc.type A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä fi
dc.description.version Peer reviewed en
dc.contributor.department University College London (UCL)
dc.contributor.department Centre of Excellence in Computational Inference, COIN
dc.contributor.department Department of Computer Science
dc.subject.keyword non-pharmacological treatment
dc.subject.keyword Postnatal depression
dc.subject.keyword primary care
dc.subject.keyword ssri treatment
dc.subject.keyword 113 Computer and information sciences
dc.subject.keyword 3142 Public health care science, environmental and occupational health
dc.identifier.urn URN:NBN:fi:aalto-201811025598
dc.identifier.doi 10.1136/bmjopen-2018-022152
dc.type.version publishedVersion


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