Title: | Algorithmic Design of Biomolecular Nanostructures |
Author(s): | Mohammed, Abdulmelik |
Date: | 2018 |
Language: | en |
Pages: | 83 + app. 89 |
Department: | Tietotekniikan laitos Department of Computer Science |
ISBN: | 978-952-60-8282-0 (electronic) 978-952-60-8281-3 (printed) |
Series: | Aalto University publication series DOCTORAL DISSERTATIONS, 219/2018 |
ISSN: | 1799-4942 (electronic) 1799-4934 (printed) 1799-4934 (ISSN-L) |
Supervising professor(s): | Orponen, Pekka, Prof., Aalto University, Department of Computer Science, Finland |
Thesis advisor(s): | Orponen, Pekka, Prof., Aalto University, Department of Computer Science, Finland |
Subject: | Computer science, Biotechnology, Physics |
Keywords: | DNA, RNA, nanotechnology, self-assembly, molecular folding, origami, graphs, surfaces, knots |
Archive | yes |
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Abstract:Biomolecular nanotechnology, a field where biomolecules such as DNA and RNA are used as programmable nanoscale construction materials, is emerging as a breakthrough technology with promising applications in nanomedicine, materials science and biophysical research. To accelerate the developments in nucleic acid nanotechnology, general and automated computer aided design tools which enable researchers from different fields to quickly design and synthesize nucleic acid nanostructures could play a significant role.
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Parts:[Publication 1]: Erik Benson, Abdulmelik Mohammed, Johan Gardell, Sergej Masich, Eugen Czeizler, Pekka Orponen, Björn Högberg. DNA rendering of polyhedral meshes at the nanoscale. Nature, 523(7561), 441–444, July 2015. Full text in Acris/Aaltodoc: http://urn.fi/URN:NBN:fi:aalto-201711217675. DOI: 10.1038/nature14586 View at Publisher [Publication 2]: Erik Benson, Abdulmelik Mohammed, Alessandro Bosco, Ana I. Teixeira, Pekka Orponen, Björn Högberg. Computer-aided production of scaffolded DNA nanostructures from flat sheet meshes. Angewandte Chemie International Edition, 55(31), 8869–8872, July 2016. Full text in Acris/Aaltodoc: http://urn.fi/URN:NBN:fi:aalto-201711217673. DOI: 10.1002/anie.201602446 View at Publisher [Publication 3]: Abdulmelik Mohammed, Mustafa Hajij. Unknotted strand routings of triangulated meshes. In Lecture Notes in Computer Science, 10467, 46–63, DNA Computing and Molecular Programming, Austin, USA, September 2017. DOI: 10.1007/978-3-319-66799-7_4 View at Publisher [Publication 4]: Erik Benson, Abdulmelik Mohammed, Daniel Rayneau-Kirkhope, Andreas Gådin, Pekka Orponen, Björn Högberg. Effects of design choices on the stiffness of wireframe DNA origami structures. ACS Nano, 12(9), 9291–9299, September 2018. DOI: 10.1021/acsnano.8b04148 View at Publisher [Publication 5]: Abdulmelik Mohammed, Pekka Orponen, Sachith Pai. Algorithmic design of cotranscriptionally folding 2D RNA origami structures. In Lecture Notes in Computer Science, 10867, 159–172, Unconventional Computation and Natural Computation, Fontainebleau, France, June 2018. DOI: 10.1007/978-3-319-92435-9_12 View at Publisher |
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