Title: | Cardiomagnetic source imaging |
Author(s): | Pesola, Katja |
Date: | 2000-05-19 |
Language: | en |
Pages: | 61, [66] |
Department: | Department of Engineering Physics and Mathematics Teknillisen fysiikan ja matematiikan osasto |
ISBN: | 951-22-5004-7 |
Subject: | Medical sciences, Physics |
Keywords: | magnetocardiography, inverse problem, equivalent current dipole, current density estimation, uniform double layer |
OEVS yes | |
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Abstract:Magnetocardiographic (MCG) source imaging has received increasing interest in recent years. With a high enough localization accuracy of the current sources in the heart, valuable information can be provided, e.g., for the pre-ablative evaluation of arrhythmia patients. Furthermore, preliminary studies indicate that ischemic areas, i.e. areas which are suffering from lack of oxygen, and infarcted regions could be localized from multichannel MCG recordings. In this thesis, the accuracy of cardiomagnetic source imaging results, obtained by using different current source models, was investigated. In addition, the effect of the torso model on the localization accuracy was examined. In some studies, also body surface potential mapping (BSPM) data were used for comparison purposes. A high impact was given to clinical validation, i.e. how the calculation methods would work in patients.
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Parts:K. Pesola, U. Tenner, J. Nenonen, P. Endt, H. Brauer, U. Leder, T. Katila: Multichannel magnetocardiographic measurements with a physical thorax phantom. Med. Biol. Eng. Comp, 37: 2-7, 1999.R. Fenici, J. Nenonen, K. Pesola, P. Korhonen, J. Lötjönen, M. Mäkijärvi, L. Toivonen, V-P. Poutanen, P. Keto, T. Katila. Nonfluoroscopic localization of an amagnetic stimulation catheter by multichannel magnetocardiography. Pacing Clin. Electrophysiol, 22: 1210-1220, 1999.K. Pesola, J. Nenonen, R. Fenici, J. Lötjönen, M. Mäkijärvi, P. Fenici, P. Korhonen, K. Lauerma, M. Valkonen, L. Toivonen, T. Katila. Bioelectromagnetic localization of a pacing catheter in the heart. Phys. Med. Biol, 44: 2565-2578, 1999.K. Pesola, J. Lötjönen, J. Nenonen, I.E. Magnin, K. Lauerma, R. Fenici, T. Katila. The effect of geometric and topologic differences in boundary element models on magnetocardiographic localization accuracy. Accepted for publication in IEEE Transactions on Biomedical Engineering, 2000.K. Pesola, J. Nenonen, R. Fenici, T. Katila. Comparison of regularization methods when applied to epicardial minimum norm estimates. Biomed. Tech, 42(S1): 273-276, 1997.K. Pesola, H. Hänninen, K. Lauerma, J. Lötjönen, M. Mäkijärvi, J. Nenonen, P. Takala, L.-M. Voipio-Pulkki, L. Toivonen, T. Katila. Current density estimation on the left ventricular epicardium: A potential method for ischemia localization. Biomed. Tech, 44(S2): 143-146, 1999.T. Oostendorp, K. Pesola. Non-invasive determination of the activation sequence of the heart: Validation by comparison with invasive human data. In: A. Murray, S. Swiryn (Eds.): Computers in Cardiology, 25: 313-316, 1998.K. Pesola, T. Oostendorp, J. Nenonen, P. Korhonen, J. Lötjönen, L. Toivonen, T. Katila. Uniform double layer solutions for magnetocardiographic and body surface potential mapping data. In: T. Yoshimoto et al. (Eds.): Recent Advances in Biomagnetism: Proceedings of the 11th International Conference on Biomagnetism, Tohoku University Press, Sendai, 290-293, 1999. |
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