Highly Diastereoselective Methylation of Five-Ring N,O-Acetals

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Journal ISSN
Volume Title
A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä
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Date
2004
Major/Subject
Mcode
Degree programme
Language
en
Pages
3
268-270
Series
LETTERS IN ORGANIC CHEMISTRY, Volume 1, issue 3
Abstract
Highly diastereoselective methylation of (2S,4S)- and (2R,4S)-3-tert-butyl 4-methyl 2-tertbutyloxazolidine-3,4-dicarboxylate (1a/b) is reported. The relative and absolute configuration of the methylated products was assigned by NOESY and confirmed by a crystal structure of 1a.
Description
Keywords
alkylation, amino acids, diastereoselectivity
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Citation
Koskinen , A M P , Brunner , M , Straub , T , Saarenketo , P & Rissanen , K 2004 , ' Highly Diastereoselective Methylation of Five-Ring N,O-Acetals ' , Letters in Organic Chemistry , vol. 1 , no. 3 , pp. 268-270 .