Unifying model of driven polymer translocation
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School of Science |
A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä
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Date
2012
Major/Subject
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Language
en
Pages
051803/1-7
Series
Physical Review E, Volume 85, Issue 5
Abstract
We present a Brownian dynamics model of driven polymer translocation, in which nonequilibrium memory effects arising from tension propagation (TP) along the cis side subchain are incorporated as a time-dependent friction. To solve the effective friction, we develop a finite chain length TP formalism, based on the idea suggested by Sakaue [Phys. Rev. E 76, 021803 (2007)]. We validate the model by numerical comparisons with high-accuracy molecular dynamics simulations, showing excellent agreement in a wide range of parameters. Our results show that the dynamics of driven translocation is dominated by the nonequilibrium TP along the cis side subchain. Furthermore, by solving the model for chain lengths up to 1010 monomers, we show that the chain lengths probed by experiments and simulations are typically orders of magnitude below the asymptotic limit. This explains both the considerable scatter in the observed scaling of translocation time with respect to chain length, and some of the shortcomings of present theories. Our study shows that for a quantitative theory of polymer translocation, explicit consideration of finite chain length effects is required.Description
Keywords
macromolecules, polymers, biopolymers, theory and modeling, polymer translocation, Brownian dynamics model, soft matter
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Citation
Ikonen, T. & Bhattacharya, A. & Ala-Nissilä Tapio & Sung, W.. 2012. Unifying model of driven polymer translocation. Physical Review E. Volume 85, Issue 5. P. 051803/1-7. ISSN 1539-3755 (printed). DOI: 10.1103/physreve.85.051803.
