Browsing by Author "Karvanen, Juha"

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    Adaptive methods for score function modeling in blind source separation
    (Helsinki University of Technology, 2002-08-26) Karvanen, Juha; Department of Electrical and Communications Engineering; Sähkö- ja tietoliikennetekniikan osasto; Signal Processing Laboratory; Signaalinkäsittelytekniikan laboratorio
    In signal processing and related fields, multichannel measurements are often encountered. Depending on the application, for instance, multiple antennas, multiple microphones or multiple biomedical sensors are used for the data acquisition. Such systems can be described using Multiple-Input Multiple-Output (MIMO) system models. In many cases, several source signals are present at the same time and there is only limited knowledge of their properties and how they contribute to each sensor output. If the source signals and the physical system are unknown and only the sensor outputs are observed, the processing methods developed for recovering the original signals are called blind. In Blind Source Separation (BSS) the goal is to recover the source signals from the observed mixed signals (mixtures). Blindness means that neither the sources nor the mixing system is known. Separation can be based on the theoretically limiting but practically feasible assumption that the sources are statistically independent. This assumption connects BSS and Independent Component Analysis (ICA). The usage of mutual information as a measure of independence leads to iterative estimation of the score functions of the mixtures. The purpose of this thesis is to develop BSS methods that can adapt to different source distributions. Adaptation makes it possible to separate sources without knowing the source distributions or even the characteristics of source distributions. Special attention is paid to methods that allow also asymmetric source distributions. Asymmetric distributions occur in important applications such as communications and biomedical signal processing. Adaptive techniques are proposed for the modeling of score functions or estimating functions. Three approaches based on the Pearson system, the Extended Generalized Lambda Distribution (EGLD) and adaptively combined fixed estimating functions are proposed. The Pearson system and the EGLD are parametric families of distributions and they are used to model the distributions of the mixtures. The strength of these parametric families is that they contain a wide class of distributions, including asymmetric distributions with positive and negative kurtosis, while the estimation of the parameters is still a relatively simple procedure. The methods may be implemented using existing ICA algorithms. The reliable performance of the proposed methods is demonstrated in extensive simulations. In addition to symmetric source distributions, asymmetric distributions, such as Rayleigh and lognormal distribution, are utilized in simulations. The score adaptive methods outperform commonly used methods due to their ability to adapt to asymmetric distributions.
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    Aerobic fitness, but not physical activity, is associated with grey matter volume in adolescents
    (Elsevier, 2019-04-19) Ruotsalainen, Ilona; Renvall, Ville; Gorbach, Tetiana; Syväoja, Heidi J.; Tammelin, Tuija H.; Karvanen, Juha; Parviainen, Tiina; University of Jyväskylä; Department of Neuroscience and Biomedical Engineering; Umeå University; LIKES Research Centre for Physical Activity and Health
    Higher levels of aerobic fitness and physical activity are linked to beneficial effects on brain health, especially in older adults. The generalizability of these earlier results to young individuals is not straightforward, because physiological responses (such as cardiovascular responses) to exercise may depend on age. Earlier studies have mostly focused on the effects of either physical activity or aerobic fitness on the brain. Yet, while physical activity indicates the amount of activity, aerobic fitness is an adaptive state or attribute that an individual has or achieves. Here, by measuring both physical activity and aerobic fitness in the same study, we aimed to differentiate the association between these two measures and grey matter volume specifically. Magnetic resonance imaging scans were used to study volumes of 30 regions of interest located in the frontal, motor and subcortical areas of 60 adolescents (12.7–16.2 years old). Moderate-to-vigorous intensity physical activity (MVPA) was measured with hip-worn accelerometers and aerobic fitness was assessed with a 20-m shuttle run. Multiple regression analyses revealed a negative association between aerobic fitness and left superior frontal cortex volume and a positive association between aerobic fitness and the left pallidum volume. No associations were found between MVPA and any brain region of interest. These results demonstrate unequal contribution of physical activity and aerobic fitness on grey matter volumes, with inherent or achieved capacity (aerobic fitness) showing clearer associations than physical activity.
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    Physical activity and aerobic fitness in relation to local and interhemispheric functional connectivity in adolescents' brains
    (John Wiley and Sons Inc., 2021-02) Ruotsalainen, Ilona; Glerean, Enrico; Karvanen, Juha; Gorbach, Tetiana; Renvall, Ville; Syvaoja, Heidi J.; Tammelin, Tuija H.; Parviainen, Tiina; Department of Neuroscience and Biomedical Engineering
    Introduction Adolescents have experienced decreased aerobic fitness levels and insufficient physical activity levels over the past decades. While both physical activity and aerobic fitness are related to physical and mental health, little is known concerning how they manifest in the brain during this stage of development, characterized by significant physical and psychosocial changes. The aim of the study is to examine the associations between both physical activity and aerobic fitness with brains' functional connectivity. Methods Here, we examined how physical activity and aerobic fitness are associated with local and interhemispheric functional connectivity of the adolescent brain (n = 59), as measured with resting-state functional magnetic resonance imaging. Physical activity was measured by hip-worn accelerometers, and aerobic fitness by a maximal 20-m shuttle run test. Results We found that higher levels of moderate-to-vigorous intensity physical activity, but not aerobic fitness, were linked to increased local functional connectivity as measured by regional homogeneity in 13-16-year-old participants. However, we did not find evidence for significant associations between adolescents' physical activity or aerobic fitness and interhemispheric connectivity, as indicated by homotopic connectivity. Conclusions These results suggest that physical activity, but not aerobic fitness, is related to local functional connectivity in adolescents. Moreover, physical activity shows an association with a specific brain area involved in motor functions but did not display any widespread associations with other brain regions. These results can advance our understanding of the behavior-brain associations in adolescents.
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    Physical activity, aerobic fitness, and brain white matter: Their role for executive functions in adolescence
    (Elsevier BV, 2020-04-01) Ruotsalainen, Ilona; Gorbach, Tetiana; Perkola, Jaana; Renvall, Ville; Syväoja, Heidi J.; Tammelin, Tuija H.; Karvanen, Juha; Parviainen, Tiina; Department of Neuroscience and Biomedical Engineering; Umeå University; University of Helsinki; LIKES Research Centre for Physical Activity and Health; University of Jyväskylä
    Physical activity and exercise beneficially link to brain properties and cognitive functions in older adults, but the findings concerning adolescents remain tentative. During adolescence, the brain undergoes significant changes, which are especially pronounced in white matter. Studies provide contradictory evidence regarding the influence of physical activity or aerobic-exercise on executive functions in youth. Little is also known about the link between both fitness and physical activity with the brain's white matter during puberty. We investigated the connection between aerobic fitness and physical activity with the white matter in 59 adolescents. We further determined whether white matter interacts with the connection of fitness or physical activity with core executive functions. Our results show that only the level of aerobic fitness, but not of physical activity relates to white matter. Furthermore, the white matter of the corpus callosum and the right superior corona radiata moderates the links of aerobic fitness and physical activity with working memory. Our results suggest that aerobic fitness and physical activity have an unequal contribution to the white matter properties in adolescents. We propose that the differences in white matter properties could underlie the variations in the relationship between either physical activity or aerobic fitness with working memory.